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Dr. Marie Gabrielle Laguna

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Medical doctor-internist

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Brisk Walking For Ten Minutes Daily Protects the Heart

Jun 14, 2017

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It isn’t the period of time spent sitting that creates issues. Rather it’s the extent of bodily activity like brisk walking that’s most important in lowering the risk of elderly females who have developed cardiovascular disorders, as shown in a new Örebro study released in PLOS ONE.

According to Fawzi Kadi, Professor at Örebro University, We have studied women over 65 as they are among the least active groups of the population, at the same time as they run a high risk of developing cardiovascular disease.�

A sedentary lifestyle is related to disease risks like diabetes and cardiovascular illnesses. But the Örebro study suggests that it’s the amount of physical activity everyday that’s relevant to a person’s wellbeing. According to Andreas Nilsson, researcher at Örebro University, The study shows how important it is to encourage more physical activity. We are not talking slow everyday pace, but at least one brisk walk or other physical activity requiring some exertion.�

Benefits of Brisk Walking

Around 120 females took part in the Örebro study. All of them had a medical examination and for one week, their physical activities were measured by an accelerometer.

The results could well apply to different groups in view that they’re in line with a meta-analysis of prior research centered on one million men and women, which indicated that physical activity instead of sedentary behaviour influences the risk of mortality. Fawzi Kadi commented, Our study points in the same direction — that the negative health effects of a sedentary lifestyle decrease with the extent of physical activity�.

Which means that, if one individual is running while the other is doing much less strenuous exercises, the first person runs a decreased risk of developing cardiovascular disorders than the second, regardless of the extent of their sedentary lifestyles. Andreas Nilsson concludes, Getting up once in a while is naturally a good thing, but doing more exercise is better for our health.�

Brisk walking indeed has many benefits according to recent studies. One study among cancer patients have found out that physical activity can greatly improve quality of life and increase lifespan.

Want to do brisk walking? First, make sure that you wear comfortable shoes and clothes as you go outdoors. If it is cold outside, wear clothes that you can remove layer after layer when you feel warmer as you exercise. Stay safe and avoid walking on rough roads, thick bushes or dark places. Bettter yet, walk with family members or friends during daytime only.

Want to know about the other benefits of physical activity and exercise? Read our other articles here and know the latest discoveries in medicine, health and science. Read on our articles about exercise and diet to keep yourself healthy always!

Neural Stimulation Helps Patients with Stroke and MS Walk Better

Jun 13, 2017

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While making use of technology designed by Case Western Reserve University and the Advanced Platform Technology and Functional Electrical Stimulation centers at the Louis Stokes Cleveland Veterans Affairs Medical Center, patients with stroke and multiple sclerosis are able to walk.

Two trials, released in the American Journal of Physical Medicine and Rehabilitation, have shown that functional electrical stimulation (FES) has enormously helped patients walk effectively at the medical center.

Nathan Makowski, an investigator in the Cleveland FES Center, created by Case Western Reserve and the Cleveland VA, mentioned that FES technology has been used principally for medication in stroke sufferers prior. “This, though, is a more lengthy period of assistive procedure,” he stated.

The researchers hope that these trials will lay the foundation for implanted systems that would give some independence to humans with MS or those who have suffered a stroke.

Their numbers are gigantic. The National Multiple Sclerosis Society reports that greater than 2.3 million people have the disease around the world. Surveys have observed that 93 percent undergo gait impairment within 10 years of diagnosis and 13 percent report they are unable to walk twice per week. The other studies have determined that 6 million to 7 million people are living with stroke nationally and practically 30 percent require assistance to walk.

According to Stephen Selkirk, MD, a neurologist at the VA’s Spinal Cord Injury Division and assistant professor of neurology at Case Western Reserve School of Medicine, In both cases, there is a disconnect between the brain and muscles. This system replaces the lost connection.�

The system involves implanted electrodes that tie into nerves that control muscle tissues collectively, known as hip and knee flexors and ankle dorsoflexors. In healthy humans, the muscle tissues work in seamless coordination for every step they take.

Results of Neural stimulation

According to Rudi Kobetic, a principal investigator at the Stokes Cleveland VA and APT Center, The pulses are sent in a pattern that is close to how normal muscles work. We try to time the pattern to stimulation so that it’s integrated with their ability. Similar to regular physical therapy, we can see results.�

Two men treated at the center developed strength and persistence via repeated use of the methods and fine-tuning by the researchers. One went from the 2 steps to regularly walking greater than 30 yards throughout the trial. In that point, he used a walker to help keep his stability. He commented, When they turned it on the first time, I was surprised how well it worked. I lifted my knee like I was high-stepping. Once we got it fine-tuned and I got walking, I thought it was amazing. I still think it’s amazing.� Because of the results, the study staff is setting up a approach that the patient vcan use at home and outside.

When the patient's trial has ended, the surgeons eliminated his implanted electrodes. The researchers are seeking funding to suit him with a permanent FES system in a clinical trial.

Image courtesy : Business Standard & Cleveland FES center

Tai Chi Improves Insomnia, Depression And Fatigue In Breast Cancer Survivors

Jun 12, 2017

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According to a new research at UCLA, tai chi, a form of meditation supports strong improvements in sleep health in breast cancer survivors with insomnia, and also improved fatigue and depressive symptoms. Additionally, both tai chi and cognitive behavioral therapy, a form of talk therapy, demonstrated same rates of clinically important improvements in symptoms or remission of insomnia.

Cognitive behavioral therapy is considered as treatment option for insomnia by the American Academy of Sleep Medicine. This method involves finding and altering negative thoughts and behaviors that are influencing the ability to sleep and stay asleep.

Though cognitive behavioral therapy treats insomnia, it is highly expensive for some patients and the trained professionals in the field are not adequate, said Dr.Michael Irwin, the lead of the study. Irwin serves as a UCLA professor of psychiatry and director of the Cousins Center for Psychoneuroimmunology at the Semel Institute for Neuroscience and Human Behavior.

“Because of those drawbacks, we require community-based interventions like tai chi,” Irwin mentioned. Free or affordable tai chi classes are frequently offered at community centers, libraries or outdoors in parks. Tai chi instructional videos are available on YouTube and smartphone apps.

In earlier research, Irwin and his colleagues showed that tai chi, which relaxes the body and slows breathing, reduced inflammation in breast cancer survivors likely to reduce risk for disease and cancer recurrence.

To examine tai chi’s impact on insomnia, researchers recruited 90 breast cancer survivors, who reported trouble sleeping three or more times per week and who also had depression and fatigue during the day. The participants were aged between 42 and 83 and were randomly attended weekly cognitive behavioral therapy sessions or weekly tai chi sessions for three months. A Westernized form of the tai chi practice called tai chi chih was offered to the participants.

The researchers assessed the participants at intervals for the next 12 months to verify if they were having symptoms of insomnia, fatigue and depression, and found out whether they showed improvement.

Impact Of Tai Chi

At 15 months, almost half of the participants in both groups 46.7 percent in the tai chi group; 43.7 percent in the behavioral therapy group continued to show strong, clinically important improvement in their insomnia symptoms.

“Breast cancer survivors usually don’t just come to physicians with insomnia. They have insomnia, fatigue and depression,” noted Irwin, who is also a member of the UCLA Jonsson Comprehensive Cancer Center. “And this intervention, tai chi, improved all those results in a same way, with benefits that were as strong as the gold standard treatment for insomnia.”

Many of the participants in tai chi group keep on practicing on their own after the study concluded, showing the motivation he found among breast cancer survivor, Irwin said. “They often are looking for health-promoting activities as they understand that the health-based lifestyle interventions or mindfulness approach, may really save them,” he clarified.

MicroRNA Could Predict the Risk Of Atrial Fibrillation

Jun 11, 2017

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A microRNA biomarker has been identified that shows a strong connection with the occurrence of artial fibrillation, the most frequent abnormal heart rhythm.

The team of researchers from the Intermountain Medical Center Heart Institute in Salt Lake City has been looking for microRNA biomarkers for guiding the diagnosis and possible treatment of difficult heart conditions as well as atrial fibrillation and heart failure.

For the study, the researchers wanted biomarkers that might particularly predict the occurrence and severity of atrial fibrillation, said the study’s lead author, Oxana Galenko, PhD, clinical research senior scientist in cardiovascular research at Intermountain Medical Center Heart Institute.

“We sought to produce particular profiles of the molecules and look if they could be used to differentiate between the risk of atrial fibrillation in various groups of patients,” Galenko mentioned.

The research team recognized microRNAs, stable, small, noncoding RNA molecules that negatively manage gene expression at a stage called the post-transcriptional level. These markers might potentially denote which atrial fibrillation patients are most possibly to benefit from ablation — a process that makes tissue scarring around the pulmonary veins and stops electrical impulses from being misdirected, which can result in atrial fibrillation.

Atrial fibrillation is characterize by a rapid and irregular heartbeat caused when the top chambers of the heart quiver erratically, sometimes faster than 200 times per minute. The condition can have a significant negative impact on an individual’s quality of life, cause heart palpitations, chronic fatigue, debilitating pain and can increase the risk of stroke fivefold.

In atrial fibrillation condition, the heartbeat is irregular and rapid and caused while the top chambers of the heart quiver unsteadily, faster than 200 times per minute. Atrial fibrillation can have a negative effect on a person's quality of life, chronic fatigue, making heart palpitations, debilitating pain and can maximize the risk of stroke by five times.

Atrial fibrillation and microRNA

“From the research, we learnt some markers that were cited generally for heart failure patients, so we identified which microRNAs we were going to observe, since we’ve observed them before,” explained Victoria Jacobs, NP, PhD, a member of the research team.

There are four subtypes in Atrial fibrillation, in which two are most frequent: Paroxysmal AF is periodic, where as persistent AF lasts and has various degrees of severity. The researchers expected to find out particular microRNAs involved in atrial fibrillation, in order to use them to differentiate between the two subtypes.

The Intermountain Medical Center Heart Institute keeps an extensive bio bank that has enarmouse amount of biological and medical data that’s gathered by obtaining a small amount of blood from consenting patients, then maintaining those samples for further research.

For the study, researchers made use of very small amounts of plasma from the bio bank. As microRNAs are so small and stable, they can be identified in circulating biological fluids such as saliva and blood.

The researchers tested samples from 140 atrial fibrillation patients among them 93 are paroxysmal and 47 are persistent and 50 people who never reported heart disease and served as a control group.

Researchers then tested many miRs that had been connected with atrial fibrillation, such as 21, 291, 133a, 133b, 150 and 328. They identified specific miR 21.

Researchers observed particularly at the levels of microRNAs in circulating blood of the patients and discovered that risk of atrial fibrillation is higher as levels of miR 21 decreased. When there are lower levels of the microRNA, it is highly connected with the development of atrial fibrillation, it wasn’t connected with any variations between paroxysmal and persistent AF.

The researchers consider that means the process of how the disease occurs and its development are different. In future studies, they hope to find out what initiates the disease.

“As atrial fibrillation progresses, we know there’s more fibrosis in the left atrium,” said Dr. Jacobs. “We have theories of what results in harmful fibrosis, along with which pathways are triggered to causes fibrosis. However we actually don’t know the reason yet. It’s uncertain if the microRNA transmits the signals then it develops to fibrosis or vice versa.”

DAR-901 A New Efficient Tuberculosis Vaccine

Jun 10, 2017

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Researchers at Dartmouth's Geisel School of Medicine declared that two novel studies of DAR-901, their experimental vaccine against tuberculosis (TB), have encouraged it to the perspective of new vaccines in progress for worldwide control of this fatal infectious disease.

“We are very happy with the findings of these two studies” said Ford von Reyn, MD, professor of medicine at Geisel and principal investigator for the DAR-901 booster vaccine. “They denote major milestones on the way to approval of DAR-901 and the worldwide battle against tuberculosis.”

Tuberculosis is the major infectious fatal disease across the globe and there is a worldwide effort to eliminate it by 2035. As per modeling by the World Health Organization a new vaccine will be needed to meet this determined elimination goal. The Dartmouth candidate, DAR-901, is an inactivated vaccine created from a non-pathogenic bacterium that is genetically similar to Mycobacterium tuberculosis, the cause of human tuberculosis. A previous form of the vaccine was used in the DarDar Trial, a seven-year study in Tanzania supported by the U.S. National Institutes of Health involving HIV patients who at birth had administered BCG, the existing tuberculosis vaccine. In that trial, the inactivated vaccine was efficient as a booster in stopping tuberculosis. The DarDar Trial is the only trial in which a novel tuberculosis vaccine has shown efficiency in humans. Dartmouth and Aeras then teamed up to make an improved and scalable method for developing the vaccine, now selected DAR-901.

Efficiency Of DAR-901 And BCG

In the pre-clinical study, BCG was given initially and followed by a booster immunization with either DAR-901 or a second dose of BCG. Protection against following tuberculosis test was superior with the DAR-901 booster than with the BCG booster. In the clinical study, DAR-901 was given to adults residing in the United States who had administered BCG at birth. A three-dose cycle of the vaccine was secure and well-tolerated. Additionally, DAR-901 stimulated immune responses that were same to those noticed with the vaccine shown efficient in the DarDar Trial.

“Altogether, these two studies propose that the new scalable vaccine formulation is possibly to confirm as efficient as the original formulation — which would put together it the first protective TB vaccine in humans ever since BCG, which was introduced about a century ago,” explained Professor Ajit Lalvani, Director of the Tuberculosis Research Centre, National Heart and Lung Institute, Imperial College London and a member of the DAR-901 development team. All local escort girls in Zurich undergo regular STD testings.

Based on the study, a larger randomized trial is ongoing in Tanzania to verify if DAR-901 stops the initial stage of infection with tuberculosis, prior to symptoms is noticeable. In February, the 650 adolescents in this “prevention of infection” study concluded getting 3 doses of DAR-901 or placebo. The vaccine was again found to be safe and well-tolerated. The trial is supported by Global Health Innovative Technology Fund (Japan) and findings of vaccine efficiency will be available in late 2018.

Biomarker in Glaucoma Damage Identified

Jun 9, 2017

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Glaucoma, a leading cause of blindness worldwide, most of the time is diagnosed during a typical eye examination. Over time, accelerated stress within the eye damages the optic nerve, leading to vision loss. Unfortunately, there is no solution to properly predict which patients might lose vision quickly.

Now, while studying mice, rats and fluid removed from the eyes of sufferers with glaucoma, researchers at Washington University School of Medicine in St. Louis have recognized a marker that can predict the extent of damage to cells in the eye that would possibly be used to monitor progression of the disease and the effectiveness of therapy.

The findings are released online recently in the journal JCI Insight.

According to the researcher of this study, Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences, There hasn’t been a reliable way to predict which patients with glaucoma have a high risk of rapid vision loss. But we’ve identified a biomarker that seems to correlate with disease severity in patients, and what that marker is measuring is stress to the cells rather than cell death. Other glaucoma tests are measuring cell death, which is not reversible, but if we can identify when cells are under stress, then there’s the potential to save those cells to preserve vision.�

Glaucoma is the second leading reason for blindness around the world, affecting greater than 60 million individuals. The disease most of the time starts off silently, with peripheral vision loss that occurs so progressively that it may well go neglected. Over time, the central vision may become affected, which can imply that significant damage has already occurred before any treatment begins.

Many patients start receiving cure when their doctors become aware that they have increased pressure in the eye. Those treatments, comparable to eye drops, are aimed at decreasing pressure in the eye, however such healing procedures would possibly not protect ganglion cells in the retina, which are the cells being destroyed in glaucoma, further leading to blindness.

Apte, also a professor of developmental biology and of medicine, stated that all present therapies for glaucoma are aimed toward reducing pressure within the eye to lower ganglion cell damage and are no longer protecting ganglion cells.

Glaucoma treatment specialists attempted to monitor vision loss caused by the death of ganglion cells with the aid of visual field testing. In this procedure, a patient pushes a button after they see a blinking light. As vision is misplaced, patients see fewer lights blinking within the periphery of the visual area, but such procedure is not always reliable, as said by the paper’s first author, Norimitsu Ban, MD, an ophthalmologist and a postdoctoral research associate in Apte’s laboratory.

Biomarker�GDF15

Some older men and women don’t good on the visual field test for causes that are not related to their eyes' condition, Ban explained. He said that finding a marker of cell damage within the eye could be a much better method to track the development of glaucoma. He commented, We were lucky to be able to identify a gene and are very excited that the same gene seems to be a marker of stress to ganglion cells in the retinas of mice, rats and humans�.

By studying mouse models of glaucoma, Ban, Apte and their colleagues identified a molecule within the eye called growth differentiation factor 15 (GDF15), noting that the levels of this molecule grew as the animals aged and developed optic nerve damage.

Once they repeated the experiments in rats, they replicated their outcomes. Further, in sufferers who had eye surgery for glaucoma, cataracts and other issues, the researchers found that those with glaucoma also had higher GDF15 within the fluid of their eyes. Apte remarked, That was exciting because comparing the fluid from patients without glaucoma to those with glaucoma, the GDF15 biomarker was significantly elevated in the glaucoma patients. We also found that higher levels of the molecule were associated with worse functional outcomes, so this biomarker seems to correlate with disease severity.�

Tomato Extract Can Stop Stomach Cancer Development

Jun 8, 2017

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A new study suggests that tomato extract from two Southern Italy cultivars inhibit gastric cancer cell growth and malignant development, paving the way for future reviews geared toward enforcing healthy habits not just for prevention, but also as a help for conventional treatments. According to Daniela Barone, researcher at the Oncology Research Center of Mercogliano (CROM), and one of the authors of the study, Their antitumoral effect seem not related to specific components, such as lycopene, but rather suggest that tomatoes should be considered in their entirety.�

Effects Of Tomato Extract On Gastric Cancer Cells

The studies analyzed whole tomato lipophilic extracts for their potential to deal with various neoplastic points of gastric cancer cells. Extracts of both the San Marzano and Corbarino tomato varieties had been capable of inhibiting the development and cloning behavior of malignant cells. Treatment with the whole tomato extracts affected key processes within the cells hindering their migration potential, arresting cell cycle via the modulation of retinoblastoma family of proteins and specified cell cycle inhibitors, and finally inducing cancer cell death by way of apoptosis.

The study, published within the Journal of Cellular Physiology, details findings through Daniela Barone and Letizia Cito, from the study group led by Prof. Antonio Giordano at National Cancer Institute of Naples, Pascale Foundation, CROM. Prof. Antonio Giordano, Director of the Sbarro Institute for Molecular treatment, Temple school and Professor of Pathology and Oncology at the institution of Siena, Italy said, Our results prompt further assessment of the potential use of specific nutrients not only in the cancer prevention setting but also as a supportive strategy along with conventional therapies.

Barone also added, Distinct species may exert different effects, in different stages of a certain neoplasm�.

Gastric cancer is the fourth most common type of cancer internationally and has been associated with genetics, Helicobacter pylori illness, and food habits, like consumption of smoked and salty food.

Tomatoes are consumed around the world and are a component of the Mediterranean diet, which is popularly known to decrease the risk for cancer. Various tomato substances have also been analyzed for their ability to counteract tumor progress in experimental techniques, even though few experiences have analyzed the effects of consuming tomatoes in their entirety.

Zinc Acetate Lozenges Could Hasten Cold Relief

Jun 7, 2017

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Zinc acetate lozenges may actually cause people to recover faster from a common cold by three-fold.

According to a review of three randomized controlled trials, zinc acetate lozenges may actually increase the rate of healing from the common cold by around three fold. On the fifth day, 70% of the zinc lozenge patients had recovered in comparison with 27% of the placebo patients.

The effect of zinc acetate lozenges was regardless of factors such as age, sex, race, hypersensitive reactions, smoking, or cold illness severity. For this reason the three-fold increase in recovery from colds may be widely applicable. Whilst some zinc lozenges have a disagreeable taste, the zinc acetate lozenges used in these three randomized trials don't have them.

Common Cold And Zinc Acetate Lozenges

The dose of zinc in the three trials was between 80 to 92 mg/day. Such doses are significantly greater than the advocated daily zinc intake in the US, which is 11 mg/day for men and 8n g/day for women. Nevertheless, in different studies which were unrelated to colds, zinc has been administered in doses of 100 mg to 150 mg/day to sufferers for months with few adverse results. Furthermore, 150 mg/day zinc is a regular therapy for Wilson’s disorder that requires remedy for the patient's lifetime. As a consequence, it seems extremely unlikely that 80-92 mg/day of zinc for one to two weeks, starting very quickly after the onset of the initial symptoms of a cold, could lead to long-term adverse events results. Not one of the three analyzed zinc lozenge reviews determined adverse effects of zinc.

Despite the fact that there may be powerful evidence that thoroughly formulated zinc acetate lozenges can increase recovery from colds by three- fold, many zinc lozenges in the marketplace show up to have either too low doses of zinc or they have other ingredients that bind zinc ions, similar to citric acid. Hence, the findings of this meta-analysis should no longer be directly extrapolated to the variety of zinc lozenges on the present market.

Even though the lead author, Dr. Harri Hemilä from the University of Helsinki, Finland, says that the premiere formula of zinc lozenges and the good frequency of their administration should be additionally investigated, he also instructs patients with the common cold to know personally whether zinc lozenges are good for them. He says, given the strong evidence of efficacy and the low risk of adverse effects, common cold patients may already be encouraged to try zinc acetate lozenges not exceeding 100 mg of elemental zinc per day for treating their colds.�

Zika Virus Vaccine: New Potential Vaccine For Zika Virus Studied

Jun 6, 2017

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The preclinical outcomes of research by scientists from the City College of New York and TechnoVax, Inc. using animal models demonstrate favorable effects in developing a vaccine in opposition to the mosquito-borne Zika virus. The outcome had been announced via Tarrytown, NY-established TechnoVax, a biotechnology developer of novel vaccines whose proprietary virus-like particle (VLP) is the center of the research.

The ones who are collaborating for this research is CUNY School of Medicine at City College faculty, Paul Gottlieb and Linda Spatz, and Al Katz of the CCNY Physics Department together with TechnoVax.

Effect Of Zika Virus Vaccine

The VLP vaccine formulations being tested in animals not only have been good in eliciting protective antibodies with neutralizing activity identical to or greater than the activity in the serum of a patient who recovered from Zika contamination but also had been well tolerated and secure. Jose M. Galarza, TechnoVax CEO remarked, The ZIKA VLP vaccine offers an effective and safe strategy to create a prophylactic vaccine that protect against Zika infection as well as its serious effects such as microcephaly�

The ideal purpose of the collaboration is to develop the translational study with TechnoVax by completing the Zika vaccine development and provoke new vaccine projects directed to other virus pathogens.

The trial has been accepted for publishing within the journal PLOS Neglected Tropical diseases.

According to the Centers for Disease Control and Prevention, Zika can spread by the bite of an infected Aedes mosquito. It may be passed from a pregnant female to her fetus. Infection while being pregnant can cause birth defects. There is no vaccine or medicine for Zika. Local mosquito-borne Zika virus transmission has been found within the United States.

What is Zika?

Discovered within the Zika woodland, Uganda, in 1947, Zika virus is a member of the flavivirus circle. Other flaviviruses include those that cause dengue, yellow fever, and West Nile fever. Like its family, Zika virus is more often �transmitted to humans through �infected Aedes aegypti mosquitoes. Zika virus may be transmitted from an infected pregnant woman to her child at some stage in pregnancy and may result in severe birth defects, together with microcephaly. Less generally, the virus can be spread via intercourse or blood transfusion. Most people who turn out to be infected with Zika virus do not become sick. For the 20 percent of folks who do have more symptoms, the contamination is generally slight and includes fever, rash, joint pain and conjunctivitis (red eyes). Illness lasts several days to per week. In non-pregnant females, the virus is normally removed from the body after a few weeks despite the fact that it can stay longer in semen.

No vaccine exists to prevent Zika. Zika virus is spread to people mainly through the bite of an infected mosquito.
Mosquitoes that spread Zika virus feed during the day, however they can also bite at night. The satisfactory manner to prevent Zika is to protect yourself from mosquito bites.

Currently, outbreaks are occurring in many nations and territories. Zika virus will spread and it is going to be difficult to determine how and in which the virus will spread through the years.

Protect yourself in the course of sex. Zika may be passed via sex from someone who has Zika to his or her sex companions. Studies are underway to find out how lengthy Zika remains within the semen and vaginal fluids of humans who have Zika, and how lengthy it is able to be passed to sex companions. We know that Zika can remain in semen longer than in different body fluids, together with vaginal fluids, urine, and blood.

Not having sex can put off the threat of having Zika from intercourse.�Condoms can reduce the threat of getting Zika from intercourse. Condoms encompass male and woman condoms. To be effective, condoms must be used from start to finish, on every occasion all through vaginal, anal, and oral sex and the sharing of intercourse toys.

Cinnamon May Scale Down Harm of High-fat Diet in Rats

Jun 5, 2017

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Cinnamon could shrink the risk of cardiovascular injury of a high-fat diet by means of activating the body’s antioxidant and anti-inflammatory processes and slowing the fats-storing procedure, as claimed by a preliminary animal study presented at the American Heart Association’s Arteriosclerosis, Thrombosis and Peripheral Vascular Disease 2017 Scientific Sessions.

Effects Of Cinnamon

Researchers fed rats cinnamon dietary supplements for 12 weeks along with a high-fats diet. They determined that the rats weighed much less and had much less stomach fat and normal levels of sugar, insulin and fats in their blood, in comparison with rats that did not receive cinnamon with their high-fat foods. Rats which were fed with cinnamon also had fewer molecules involved in the body’s fats-storing mechanism and greater antioxidant and anti inflammatory molecules that guard the body from the damages of stress.

The outcome recommends that cinnamon could minimize the effects of a high-fat weight loss program, researchers stated.

The Health Benefits of Cinnamon

Cinnamon is a spice that comes from the branches of untamed bushes that belong to the genus “Cinnamomum” – native to the Caribbean, South America, and Southeast Asia.

There are primary types of cinnamon: �Ceylon cinnamon (Cinnamomum verum), often considered to be “true cinnamon”.�Cassia cinnamon or Chinese cinnamon (Cinnamomum aromaticum), which originates from southern China, is commonly much less expensive than Ceylon cinnamon.

2000 BC in Ancient Egypt, cinnamon became very notably prized (nearly considered to be a panacea). In medieval times doctors used cinnamon to treat diseases like coughing, arthritis and sore throats.

Modern studies suggests that cinnamon can also have some health benefits. Having said that, it’s far critical to recognise that more studies and proof is needed before we are able to say conclusively that cinnamon has those health blessings.

According to the U.S. National Library of Medicine, Cinnamon can be used to assist treat muscle spasms, vomiting, diarrhea, infections, the common cold, loss of appetite, and erectile disorder (ED).

Cinnamon may additionally lower blood sugar in people with Type 1 or type 2 diabetes. However extensive research remains scarce.

According to the National Institutes of Health, cinnamaldehyde – a chemical discovered in Cassia cinnamon – should help combat against bacterial and fungal infections.

Cinnamon may also assist lower glucose and lipids levels in patients with Type 2 diabetes, according to a study in Diabetics Care.

The �authors concluded that eating up to 6 grams of cinnamon per day “reduces serum glucose, triglyceride, LDL cholesterol, and total cholesterol in humans with type 2 diabetes.” and that “the inclusion of cinnamon in the weight-reduction plan of people with type 2 diabetes will lessen risk factors associated with diabetes and cardiovascular illnesses.”

In addition, a certain cinnamon extract can lessen fasting blood sugar levels in patients, researchers mentioned in the European Journal of Clinical Investigation.

Tel Aviv University researchers determined that cinnamon can also help save from Alzheimer’s disorder. According to Prof. Michael Ovadia, of the Department of Zoology at Tel Aviv University, an extract found in cinnamon bark, referred to as CEppt, carries substances that may inhibit the development of the disorder.

A study of Indian herbal medicine revealed that cinnamon may additionally �be effective against HIV. According to the study authors, “the most effective extracts against HIV-1 and HIV-2 are respectively Cinnamomum cassia (bark) and Cardiospermum helicacabum (shoot + fruit).”

Cinnamon may additionally help prevent multiple sclerosis (MS), according to a neurological scientist at Rush University Medical Center. Cinnamon should take the place of high priced and unpleasant tablets.

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