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Dr. Marie Gabrielle Laguna

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Medical doctor-internist

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Flu Nasal Sprays Can Protect People from Flu, Like Flu Shots

Sep 21, 2016

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A recent study led by McMaster college researchers has found out that, contrary to contemporary experiences, flu nasal sprays provide an identical safeguard against influenza as regular flu shots.

Released in the scientific journal Annals of Internal medicine, the study indicates that the nostril spray had a identical outcomes to the ordinary flu shot. Prior recommendations from the Centers for Disease Control’s Advisory Committee on Immunization Practices (ACIP) had beforehand called for nasal sprays, or live attenuated influenza vaccine (LAIV), that they should no longer be used for the duration of the 2016-2017 flu season. Dr. Mark Loeb, lead author of this study, says his staff’s findings presently challenge the ACIP’s strategies to flu shots, or inactivated vaccines.

According to him, Our study is the first blinded randomized controlled trial to compare the direct and indirect effect of the live vaccine versus the inactivated vaccine. Our results are important because in previous years the live vaccine had first been preferred for children. In fact, as late as June 2014, the live vaccine was preferred. Then, subsequently, it was no longer preferred and now not recommended at all. Our trial showed no difference between the two in protecting entire communities.�

In this study, Loeb’s workforce performed a three-year trial in a Hutterite colony, where individuals reside communally and are moderately remoted from cities and cities, to determine whether or not vaccinating kids and youth with the flu nasal spray provided better direct and group defense than the common flu shot.

The researchers randomly assigned 1,186 children in 52 Hutterite colonies in Alberta and Saskatchewan, Canada to receive both the nasal spray vaccine and the flu shot and in addition followed 3,425 community participants who didn’t acquire a flu vaccine. Average vaccine coverage among children in the nasal spray group was once 76.9% versus 72.3% in the flu shot group.

The long-established intention of the study was to exhibit that nasal spray vaccines would provide better security than flu shots, but Loeb says the conclusions of the study are actually important, given the ACIP’s strategies. He further remarked, The ACIP’s decision was an unprecedented decision in influenza vaccine policy-making for children. Our study challenges previous studies because our results show conclusively that the vaccines show similar protection when both direct and indirect effects are taken into account.�

Loeb says that his crew will proceed to study herd immunity with special vaccine formulations by vaccinating youngsters. They’re also looking at the outcome of repeated vaccination of children.

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BPA Exposure in Pregnancy Leads to Anxiety and Depression in Boys

Sep 20, 2016

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Boys who were exposed prenatally to BPA, a chemical utilized in plastics could be more likely to display signs of anxiety and depression at age 10-12. The new study made by researchers at the Columbia Center for Children’s Environmental Health (CCCEH) inside the Mailman School of Public Health examined the effects of early exposure to the chemical Bisphenol A (BPA). The outcomes are published in the journal Environmental Research.

BPA is present in some plastics and is found in meal containers, plastic water bottles, dental sealants, and thermal receipt paper. In the body, BPA is a synthetic estrogen, probably the most type of chemical compounds referred to as “endocrine disruptors.” The Columbia researchers, led by Frederica Perera, PhD, DrPH, director of CCCEH, earlier said that prenatal exposure to BPA was once related to emotionally reactive and aggressive behavior, and symptoms of nervousness and depression in boys at age 7-9.

Perera and her co-researchers studied 241 nonsmoking pregnant women and their kids, a subset of CCCEH’s longstanding urban birth cohort study in New York City, from pregnancy through childhood. To measure the amount of BPA that had been absorbed within the body, researchers accrued a urine sample from the moms during the 1/3 trimester of their being pregnant, and from the kids at age 3 and age 5. At ages 10-12, children accomplished an interview with a researcher about their signs of depression and completed a self-evaluation that measures anxiousness.

Researchers managed for reasons that have been beforehand associated with BPA exposure stages, including socioeconomic explanations. They found that boys with the highest levels of prenatal exposure to BPA had extra symptoms of depression and anxiety than boys with decreases prenatal exposure to BPA; no such associations were found in girls.

According to neuropsychologist and co-investigator Amy Margolis, PhD, assistant professor of Medical Psychology in Psychiatry at Columbia University Medical Center, These findings are consistent with our prior reports on BPA and children’s development assessed at earlier ages and suggests greater susceptibility of the male brain during prenatal development. Anxiety and depression are particularly worrisome because they can interfere with a child’s ability to concentrate, perform in school, socialize and make friends�.

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Taking Calcium Supplements May Bring Dementia, Studies Show

Sep 19, 2016

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Consistent with a new study, calcium supplements may be associated with an extended risk of dementia in older women who have had a stroke or other signs of cerebrovascular disease. The study is released in the August 2016 issue of Neurology, the medical journal of the American Academy of Neurology.

Cerebrovascular disease is a gaggle of disorders that have an impact on blood flow in the brain. These ailments, together with stroke, are the fifth leading causes of death in the United States and increase the threat of dementia. According to the study author Silke Kern, MD, PhD with the University of Gothenburg in Sweden, Osteoporosis is a common problem in the elderly. Because calcium deficiency contributes to osteoporosis, daily calcium intake of 1000 to 1200 mg is recommended. Getting this recommended amount through diet alone can be difficult, so calcium supplements are widely used. Recently, however, the use of supplements and their effect on health has been questioned.�

This study involved 700 dementia-free females between the ages of 70 and 92 who were followed-up for 5 years. Participants took tests on the beginning and end of the trial, together with exams of memory and cognition skills. A CT brain scan was then performed in 447 participants on the start of the study.

Scientists also checked out the use of calcium dietary supplements in the individuals and whether or not they have been diagnosed with dementia over the course of the trial. A total of 98 females were taking calcium dietary supplements on the start of the study and 54 women had already developed a stroke. During the trial, 54 more women had strokes, and 59 ladies developed dementia. Among the many females who had CT scans, 71% had lesions on their brains’ white matter, which is a marker for cerebrovascular disorder.

The study observed that the women who were treated with calcium supplements were twice as likely to have dementia as the women who did not take supplements. But when the researchers additionally analyzed the information, they observed that the higher risk was best among women with cerebrovascular disease.

Women with a history of stroke who took dietary supplements had a practically seven times extended chance of having dementia than women with a past history of stroke who did not take calcium supplements. Women with white matter lesions who took dietary supplements were thrice as prone to develop dementia as women who had white topic lesions and did not take dietary supplements. Women without a history of stroke or women without white matter lesions had no improved chance when taking calcium supplements.

In summary, 14 out of 98 females who took dietary supplements developed dementia, or 14%, in comparison with 45 out of 602 women who didn’t take dietary supplements, or 8%. A total of 6 out of 15 females with a history of stroke who took supplements developed dementia, compared to 12 out of 93 women with a history of stroke who did not take dietary supplements. Among the many women with no past history of stroke, 18 out of eighty three who took dietary supplements developed dementia, in comparison with 33 out of the 509 who did not take supplements.

According to author, It is important to note that our study is observational, so we cannot assume that calcium supplements cause dementia�.

The author also noted that the study was small and that outcome cannot be generalized to the total population, and extra studies are wanted to verify the findings. He further said that calcium from food influences the body in another way than calcium from supplements and appears to be trustworthy or even protective in opposition to vascular issues.

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Anemia After Stroke Most Like to Lead to Death

Sep 18, 2016

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Anemia, a condition marked by a decrease in red blood cells, is also linked to a higher hazard of dying in older adults who have had a stroke. This is consistent with new research in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Anemia is more common among sufferers with acute stroke. Anemia and low haemoglobin levels, which are proteins in red blood cells that carry oxygen in the body, are also common in older individuals, stated Phyo Myint, M.D., the senior author of the study and the Professor of Medicine of Old Age at the University of Aberdeen in Scotland.

Researchers examined data from 8,013 hospital sufferers, with an average of 77 years old, admitted with acute stroke between 2003 and 2015. Researchers assessed the impact of anemia and hemoglobin levels on death at different time points up to one year following stroke. They soon found out that anemia was present in a quarter of sufferers with stroke upon admission and was associated with a greater hazard of dying for up to one year following either ischemic stroke (clotted blood vessel) or hemorrhagic stroke (ruptured blood vessel).

Additionally, accelerated hemoglobin levels have been associated with poorer effects and a higher threat of death, most likely within the first month following stroke, meaning each low and high levels of hemoglobin could be related to a better risk of demise after stroke. According to the author of this study, We found that the likelihood of dying from ischemic stroke is about two times higher in people with anemia compared to those without it, and the risk of death from hemorrhagic stroke is about 1.5 times higher. So there’s the potential for a much poorer outcome if somebody comes in with stroke and they’re also anemic.�

“We determined that the possibility of loss of life from ischemic stroke is set two occasions higher in persons with anemia compared to those with out it, and the risk of demise from hemorrhagic stroke is about 1.5 instances larger,” Myint said. “So there is the expertise for a so much poorer final result if a person comes in with stroke and so they’re also anemic.”

Additionally to the U.K. Regional Stroke Registry, the researchers systematically reviewed important literature published to this point. They used 20 previous studies to conduct one larger study through compiling data from a vast variety of countries, growing the study population to 29,943 stroke sufferers. This further quantified the impact of anemia and improved the generalizability of the findings, researchers stated.

Researchers supposed that the study emphasizes the influence of anemia on stroke results and the necessity for extended realization and interventions for stroke patients with anemia. According to Raphae Barlas, co-author and medical student at the University of Aberdeen, One example of an intervention might be treating the underlying causes of anemia, such as iron deficiency, which is common in this age group. As the study has convincingly demonstrated, anemia does worsen the outcome of stroke, so it is very important that we identify at-risk patients and optimize the management.�

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Natural Product from Sea Sponge Can Treat Pancreatic Cancer

Sep 17, 2016

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Scientists from the Florida Atlantic University’s Harbor Branch Oceanographic Institute have recently determined that a deep-water marine sponge accrued off of Fort Lauderdale’s coast comprises leiodermatolide, a natural product that has the ability to inhibit the growth of pancreatic cancer cells and its spread utilising particularly low concentrations of the compound.

This work resulted into the awarding of a patent from the U.S. Patent and Trademark Office that protects the usage of the compound against some cancers.

Sea sponges are an historical group of animals that appeared more than 600 million years in the past and have the same genes as humans. These scientists want to take advantage of this similarity in human and sponge genomes to isolate marine common compounds from these organisms to strengthen the development of drugs which may be useful in the cure of human diseases such as cancers. The researchers are increasing their customary findings, not too long ago showing that leiodermatolide can reduce pancreatic tumor size in vivo, publishing the results of this study in the International Journal of cancer (IJC).

Pancreatic cancer is the fourth main cause of cancer deaths in the USA. Pancreatic cancer patients have less than 7 percent survival rate within five years of diagnosis, and 74% of patients die within the primary year of diagnosis. Recently, pancreatic melanoma has received greater concentration given that many famous individuals have died from the disorder.

In this article in IJC titled, “Leiodermatolide, a Novel Marine Natural Product, Has powerful Cytotoxic and Antimitotic Activity Against Cancer Cells, Appears to Affect Microtubule Dynamics, and Exhibits Antitumor Activity,” the researchers more entirely outline how this marine compound kills cancer cells, and exhibit that its results not only occur against cells however it additionally has the potential to decrease pancreatic cancer tumor weight.

The lead author of the study is Esther GuzmÃ�n, Ph.D. associate research professor at FAU Harbor Branch, and the other co-authors are Amy Wright, Ph.D., research professor; Tara Pitts, biological scientist; and Priscilla Winder, Ph.D., research associate; as well as collaborators from Eisai Pharmaceuticals and the University of Central Florida. their study was able to exhibit that leiodermatolide induces programmed cell death in pancreatic cancer cells, and inhibits the progress of other cancer cells reminiscent of metastatic melanoma, colon cancer, lymphoma, and glioblastoma, a infrequent and deadly form of brain cancer.

The normally used anti-cancer drug, Taxol™, works by interacting with tubulin and inflicting its polymerization. Leiodermatolide also interacts with tubulin but appears to affect microtubule dynamics by a particular mechanism of action in comparison with different microtubule interacting agents. In a mouse model of metastatic pancreatic melanoma, leiodermatolide exhibited enormous tumor reduction in comparison with gemcitabine — the common drug for pancreatic cancer and controls.

According to the lead author, Given the uniqueness of its mechanism of action, its potency, its selectivity for cancer cells, and its in vivo efficacy, leiodermatolide is an extremely interesting compound that merits further studies to determine its therapeutic potential for addressing some of the most devastating forms of cancer�.

Another author remarked, The primary goal of our marine biomedical and biotechnology program is to discover marine natural products with utility as medicines or as tools to better allow us to understand disease processes�.

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Omega-3 Fatty Acids Can Lower Risk For Diabetic Retinopathy

Sep 16, 2016

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In middle-aged and older people with type 2 diabetes, consuming at least 500 mg per day of dietary long-chain omega-3 polyunsaturated fatty acids, readily attainable with two weekly servings of oily fish, was associated with a lower risk for sight-threatening diabetic retinopathy, according to a recent journal article published in JAMA Ophthalmology.

The increasing incidence of type 2 diabetes mellitus, coupled with an increased lifespan, has resulted in a consistent increased risk of disability in older people with diabetes. A foremost obstacle for this group is diabetic retinopathy (DR), a main cause of blindness. Given the monetary and societal burden of DR, establishing effective systems to avoid or at least prolong its onset is a predominant concern. The retina is rich in long-chain omega-3 polyunsaturated fatty acids. Experiments support dietary LC-PUFA defense towards DR, but clinical knowledge are lacking.

The main author of this study, Aleix Sala-Vila, D.Pharm., Ph.D., of the Lipid Clinic, Barcelona and colleagues performed a prospective study inside the randomized scientific trial Prevencion con Dieta Mediterranea (PREDIMED). In this study, they tested Mediterranean diets supplemented with extra virgin olive oil or nuts versus a control food regimen for essential cardiovascular prevention.

The trial was conducted in major health care facilities in Spain. From 2003 to 2009, 3,614 contributors aged 55 to 80 years with an earlier diagnosis of type 2 diabetes had been recruited. Full knowledge has been available for 3,482 participants (48% men; average age 67 years). Meeting the dietary LC-omega-3-3PUFA suggestion of at the least 500 mg per day for essential cardiovascular prevention was assessed by a validated food-frequency questionnaire.

Of the individuals, a total of 2,611 (75%) met the goal LC-omega-3PUFA recommendation. For the duration of the median follow-up of 6 years, incident DR was identified in 69 of the study subjects. After adjusting for age, sex, intervention group, and lifestyle and clinical variables, individuals meeting the LC-omega3PUFA suggestion at baseline (500 mg/d or better) when compared with those no longer fulfilling this recommendation (lower than 500 mg/d) showed a 48% relatively lowered risk of incident sight-threatening DR.

The authors wrote Our findings, which are consistent with the current model of the pathogenesis of DR and data from experimental models, add to the notion of fish-derived LC?3PUFA as a healthy fat.�

The PREDIMED study provides thoughts for individuals who desire to fight the issues of diabetes by means of clever eating, writes Michael Larsen, M.D., D.M.Sc., of Rigshospitalet-Glostrup and University of Copenhagen, Glostrup, Denmark, in an accompanying commentary. It seems a safe bet now to spread one’s food intake to include the gifts of our oceans and forests, while we consider how they can be protected for future generations and wait for large and ambitious studies of the effects of diet on diabetic retinopathy. The success of such studies in age-related macular degeneration shows that solid scientific information is worth waiting and working for.�

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New Sunscreen Compound Can Offer Cell Protection Against UVA Radiation

Sep 15, 2016

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UVA Radiation

A new substance developed by scientists in the University of Bath scientists in collaboration with King’s College London offers new and effective protection against the damaging effects of UVA radiation ifrom sunlight, which leads to fast aging, cancers and cell damage.

Most sunscreens on the market can shield well against solar UVB radiation but have restricted effectiveness against UVA injury, thus only counting on the reflective properties of creams to safeguard against detrimental UVA rays.

Nevertheless this new compound, referred to as the ‘mitoiron claw’ by the group, offers robust protection inside our cells precisely in the place where the greatest damage from UVA happens, and would not intervene with the other activities of the cell.

The Mitoiron Claw

The researchers from the University of Bath, working with colleagues at Kings College London, hope to see the mitoiron claw compound introduced to sunscreens and skin care products in 3 to 4 years time.

Free iron concentration is in particular high inside the mitochondria, the batteries of the cell, where it is wanted for some capabilities. Nonetheless upon exposure to UVA in the sunlight, excess free iron acts as a catalyst for the construction of toxic reactive oxygen species (ROS), causing damage to cell components such as DNA, fat and proteins thereby increasing the chance of cancer and cell death.

Nonetheless this custom-designed iron chelator (a molecule that binds to an iron atom like a claw) strikes straight to the mitochondria where it safely binds the excess free iron, stopping it from reacting upon exposure to UVA rays.

Lab exams with human dermis fibroblast cells exposed to UVA radiation for 140 minutes of uninterrupted solar exposure at sea level showed that cells treated with the mitoiron claw were completely protected against death. Untreated cells died.

The study is published within the Journal of Investigative Dermatology. One of the authors, Dr Charareh Pourzand, from the Department of Pharmacy and Pharmacology at the University of Bath, said, The role of iron-mediated damage induced upon exposure of skin cells to UVA has been underestimated for many years. For efficient protection against UVA-induced iron damage of skin strong chelators are needed, but until now these risked toxic effects caused by non-targeted iron starvation of cells. Our mitochondria-targeted compound provides a solution to this problem and can address an unmet need in the skincare and sunscreen fields. This mitoiron claw is a highly effective compound, offering unprecedented protection against UVA-induced mitochondrial damage.�

Now that the protective effects of the substance were verified the researchers, Dr Charareh Pourzand and Dr Olivier Reelfs from the University of Bath and Prof Robert Hider and Dr Vincenzo Abbate at Kings College London, plans more work to discover the effects of this new compound. This entails the likelihood of establishing cures for ailments involving mitochondrial iron overload, such as Friedreich’s ataxia.

If you want to know more on how to take care of your health the best way possible, feel free to read our other articles on this site.

Reference: Science Daily

Written By: Dr. Marie Gabrielle Laguna Bedia

Early Stage Alzheimer’s disease Can Be Diagnosed Through The Eyes

Sep 13, 2016

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Early Stage Alzheimer’s Disease Through Eyes

Investigators at the Cedars-Sinai Regenerative Medicine Institute have found out certain eye abnormalities that will support the diagnosis of early-stage Alzheimer’s disease. Utilizing a novel laboratory rat model of Alzheimer’s disease and imaging methods with high resolution, researchers correlated variations of these eye structures, to identify preliminary characteristics of the disorder.

Alzheimer’s disease is the main reason of dementia, which is characterized by loss of memory and a progressive decline in cognitive thinking. Up to now, greater than 26 million persons are estimated to suffer from this illness and the quantity is predicted to quadruple by 2050. Despite the sickness being described over a century in the past, medication and understanding of this disease stay limited.

The lead author of the study, Shaomei Wang, MD, PhD, and an associate professor in the Regenerative Medicine Institute and Department of Biomedical Sciences remarked, Detecting changes in the brain that indicate Alzheimer’s disease can be an extremely challenging task. “By using the eye as a window to brain activity and function, we may be able to diagnose patients sooner and give them more time to prepare for the future. Options may include earlier enrollment in clinical trials, developing support networks and dealing with any financial and legal matters.�

Retinal Pigment Epithelial Layer Changes

Utilising animal models and postmortem human retinas from donors with Alzheimer’s disease, researchers found alterations in the retinal pigment epithelial layer, which harbors the supportive cells placed in the back of the eye, and in the thickness of the choroidal layer with blood vessels offering vitamins and minerals to the retina. Changes in these two regions had been detected utilizing sophisticated, modern day imaging and immunological strategies.

With high-resolution microscopic imaging and visible acuity measurements, investigators had been capable of watching tissue degeneration within the cell layer and vascular layer behind the eye, along with a decline in visual function that had been strongly associated with Alzheimer’s disorder.

According to the co-author of the study, Alexander Ljubimov, PhD, director of the Eye Program within the Regenerative Medicine Institute, Greater magnitude in these eye abnormalities may mean a greater chance of a patient having Alzheimer’s disease. We found that a rat model showed similar signs to the human ailment in the eye. If true in a larger number of humans, these findings may be used to study Alzheimer’s disease mechanisms and test potential drugs.�

Although additional research is required to examine the mechanisms of those ocular changes in terms of changes in the brain, investigators hope to eventually help in the early diagnosis of Alzheimer’s disorder via studying the eye. Cedars-Sinai had done previous studies on the eye and Alzheimer’s disease with a previous report displaying amyloid plaques, an indicator of Alzheimer’s sickness, additionally build up within the eye making use of a similar animal model of the disease.

According to Clive Svendsen, PhD, director of the Cedars-Sinai Regenerative Medicine Institute and a co-author on the study, It is fascinating that the eye may provide such a window to the brain and eventually predict diseases such as Alzheimer’s, although more human studies are now needed to confirm this animal work�

If you want to know more on how to take care of your health the best way possible, feel free to read our other articles on this site.

Reference: Science Daily

Written By: Dr. Marie Gabrielle Laguna Bedia

Too Much Work Can Lead to Mental Problems

Sep 12, 2016

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Too Much Work Is Not Good

Workaholism mainly co-occurs with ADHD, OCD, nervousness, and despair. These are the results of a significant country-wide Norwegian study. The study showed that workaholics scored higher on all the psychiatric symptoms than non-workaholics.

Researchers on the University of Bergen in Norway have studied the relationship between workaholism and psychiatric issues amongst 16,426 adults. According to researcher and Clinical Psychologist Specialist Cecilie Schou Andreassen, at the Department of Psychosocial Science, at the University of Bergen (UiB), and visiting scholar at the UCLA Semel Institute for Neuroscience and Human Behavior, Workaholics scored higher on all the psychiatric symptoms than non-workaholics�.

Workaholics score higher on all symptoms

The results showed that workaholics scored higher on all of the psychiatric symptoms than those who are non-workaholics. Among workaholics, the principal findings had been that 32.7 percent met ADHD criteria (12.7 percent among non-workaholics), 25.6 percent met OCD criteria (8.7 percent amongst non-workaholics) and 33.8 percent met anxiety standards (11.9 percent amongst non-workaholics). In this study 8.9 percent met depression criteria (2.6 percent among non-workaholics).

The author noted, Thus, taking work to the extreme may be a sign of deeper psychological or emotional issues. Whether this reflects overlapping genetic vulnerabilities, disorders leading to workaholism or, conversely, workaholism causing such disorders, remain uncertain.�

The results of this study are released in the open-access journal PLOS One, and are co-authored by researchers from Nottingham Trent University and Yale University.

Schou Andreassen further says that the findings clearly spotlight the importance of additionally investigating neurobiological deviations regarding workaholic behaviour. In wait for more research, physicians should not take for granted that a seemingly successful workaholic does not have ADHD-related or other clinical features. Their considerations affect both the identification and treatment of these disorders�.

According to this study, the seven diagnostic criteria for workaholism are thinking of how you can free up more time to work, spending much more time working than initially intended, working in order to reduce feelings of guilt, anxiety, helplessness or depression; being told by others to cut down on work without listening to them, becoming stressed if you are prohibited from working, deprioritizing hobbies, leisure activities, and/or exercise because of your work and working so much that it has negatively influenced your health. Scoring 4 (often) or 5 (always) on four or more criteria identify a workaholic.

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Enriched Hops Extract Can Treat Breast Cancer

Sep 11, 2016

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Hops Can Prevent Breast Cancer

An enriched hops extract activates a chemical pathway in cells that could aid in the prevention of breast cancer, according to new laboratory findings from the UIC/NIH Center for Botanical Dietary Supplements Research at the University of Illinois at Chicago.

Natural plant dietary supplements similar to hops have ended up more preferred among females for postmenopausal symptom relief, as they are perceived as a safer alternative to hormone therapy, which has been linked to accelerated hazard of breast cancer. However, the efficacy and toxicity of botanicals are still being studied.

The research team led by Judy Bolton, professor and head of medicinal chemistry and pharmacognosy within the UIC College of Pharmac, utilized hops extract to 2 different breast cell lines to see if they might impact estrogen metabolism, a key mechanism in breast cancer. One compound, 6-prenylnarigenin, or 6-PN, stimulated a pathway in the cells that has been linked to a reduced risk for breast cancer. According to Bolton, We need to further explore this possibility, but our results suggest that 6-PN could have anti-cancer effects�.

Moreover, Bolton and the other researchers studied 8-prenylnarigenin (8-PN), isoxanthohumol (IX) and xanthohumol (XH) for their effects on estrogen metabolism in the breast cells. According to her, 8-PN showed little increase of metabolism in breast cells, at the same time while the other two compounds did not have great results in either cell line.

Breast Cancer

Breast cancer is without doubt one of the mostly identified cancers in women within the U.S. It is said that about one in eight U.S. women will develop invasive breast cancer over their lifetime. An estimated 246,660 new instances of invasive breast cancer and 61,000 new circumstances of non-invasive breast cancer are anticipated in women within the U.S. annually, according to the American Cancer Society.

The incidence of breast cancer started out lowering in the year 2000, after increasing during the previous twenty years. From 2002 to 2003, the incidence declined by 7%. Some believe the drop was partly due to lowered use of hormone replacement treatment, or HRT, after the Women's Health Initiative study suggested a link between HRT and expanded breast cancer risk. Exposure to estrogen has long been linked with postmenopausal breast cancer chance, especially based on the 2002 document.

The results of this study are published within the journal Chemical Research in Toxicology.

If you want to know more on how to take care of your health the best way possible, feel free to read our other articles on this site.

Reference: Science Daily

Written By: Dr. Marie Gabrielle Laguna Bedia

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