Comments on: Researchers Explain How Ketamine Improves Depression Within Minutes After The First Dose

By: skintagsremoval

skintagsremoval — Sun, 07 Jul 2013 13:50:54 +0000

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By: Home Coffee Machines

Home Coffee Machines — Mon, 06 May 2013 14:59:04 +0000

Today, I went to the beach front with my children.
I found a sea shell and gave it to my 4
year old daughter and said “You can hear the ocean if you put this to your ear.” She placed the shell to
her ear and screamed. There was a hermit crab inside and it pinched her ear.
She never wants to go back! LoL I know this is entirely off topic but I had
to tell someone!

By: Dorthea Glenn

Dorthea Glenn — Fri, 16 Nov 2012 11:40:32 +0000

Genius and Someone–I just have to laugh and agree. In addition to knives, almost any over-the-counter drug, if taken in large enough quantities, can kill a person. Nobody used the word “gun” either, but you can see where that line of thought leads.

By: Dorthea Glenn

Dorthea Glenn — Fri, 16 Nov 2012 11:33:50 +0000

In reply to Christopher Steffen. Thanks for clarifying, Christopher Steffen! Still, in acute cases of clinical depression, such as would be treated by ECT in combination with other medication(s), it sounds to me like ketamine, administered in an inpatient or doctor's office setting, would be a better, less invasive and risky choice than ECT (which I don't think has ever been FDA-approved for treatment of depression). Also, many other commonly used drugs for depression also are used as recreational drugs and have a high abuse potential, such as ritalin and Provigil. If administered judiciously directly by a doctor/nurse in a clinic (assuming you don't need to take it daily), it sounds fairly safe to me. Which brings up another point: what is the dosing schedule? Does one treatment permanently cure the test mice or do they need follow-up doses? I look forward to reading more about about this potential treatment in future articles!

By: Genius

Genius — Thu, 25 Oct 2012 12:41:01 +0000

In reply to Someone.

Just let me leave it here, quote from Thomas Szasz considering all drugs:
“It isn’t just heroin and marijuana that are illegal — EVERY drug in America that’s any good is illegal, because if you have to go to a doctor to get a prescription to get a drug, ladies and gentlemen, it’s illegal. The medical people have forgotten this because we all get drugs like people in Russia (then the Soviet Union) have to get permission to emigrate.”

By: Someone

Someone — Thu, 25 Oct 2012 12:35:56 +0000

In reply to Genius. Can't you see? Murderers are clearly so much better than getting 15-20% of population into better mental health!

By: Genius

Genius — Thu, 25 Oct 2012 12:34:00 +0000

Knives have abuse potential, why anyone can buy one in every supermarket?! Ethicst retards.

By: Anonymous

Anonymous — Tue, 23 Oct 2012 22:48:12 +0000

Ketamine is a fantastic drug!

By: Christopher Steffen

Christopher Steffen — Tue, 23 Oct 2012 17:31:42 +0000

Ketamine is not considered a suitable antidepressant on its own righ due to the abuse potential. It has been used frequently as a recreational drug and had addictive potential. Thus, they are searching for a new substance with similar antidepressant effects but less abuse potential.

By: Dorthea Glenn

Dorthea Glenn — Tue, 23 Oct 2012 10:40:00 +0000

“Researchers have managed to reproduce the effects of ketamine in newly developed drugs, however, the action of the new drugs is slower than that of ketamine. Researchers are currently trying to identify alternative ways to duplicate the effectiveness of ketamine.” I don’t understand. What’s wrong with just using ketamine? Why do they need to understand how it works before developing drugs with similar effectiveness? They don’t know how any of the other antidepressants work that are on the market. And, with all of the clinical trials and if ketamine is a known child anesthetic, it must be quite safe.

Why isn’t ketamine a very common treatment for this group of patients who cannot be helped by anything else? Perhaps in the future they will discover more/better treatments, but until then why not use the ketamine? I didn’t see any reasons cited in the article for why it isn’t being used already for this purpose…