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For people who suffer from various psychiatric and neurological conditions, brain stimulation has become an increasingly important treatment option in the recent decades.

Deep Brain Stimulation

Deep Brain Stimulation

Brain simulation techniques can be divided into two broad categories, invasive and noninvasive. Both of them work by targeting specific sites in the brain to adjust the overall brain activity. Among the most well-known invasive techniques is the deep brain stimulation (DBS) which requires a brain surgery and is approved by the U.S. Food and Drug Administration (FDA). This process is typically used for treated Parkinson's disease and this process requires an electrode to be inserted in the brain. Among the noninvasive techniques is the transcranial magnetic stimulation (TMS) which can be administered from outside the head. This treatment is currently approved for treating depression.

Brain stimulation has resulted in dramatic benefits to patients with such disorders, which has motivated researchers to test if it can be useful in treated patients suffering from other diseases. The problem is that doctors have been unable to pinpoint which are the ideal sites to administer simulation in a given patient for a given condition.

A new study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) in the Proceedings of the National Academy of Sciences (PNAS) suggest that brain networks which consists of the interconnected pathways that link brain circuits to one another can assist in selection of ideal spot for brain stimulation therapies.

Michael D. Fox, MD, PhD, First author of the study, an investigator in the Berenson-Allen Center for Noninvasive Brain Stimulation and in the Parkinson’s Disease and Movement Disorders Center at BIDMC remarked that although different types of brain stimulation are currently applied in different locations, it has been found that the targets used to treat the same disease are nodes in the same connected brain network. This can have a direct implication on how brain stimulations are administered to treat diseases.

For example, in order use brain stimulation to treat Parkinson’s disease or tremor an electrode need to be inserted deep in the brain. Getting the same effect with noninvasive stimulation is difficult, as the spot is deep in the brain. However, by looking at the brain’s network connectivity, sites can be identified on the surface of the brain that is connected with the deep spot site. Hence, that deep spot can also be stimulated noninvasively.

For this study Fox's team conducted a large-scale literature search to find out all neurological and psychiatric diseases where brain stimulation via both invasive and non-invasive techniques had shown improvement. The search found 14 such conditions namely addiction, Alzheimer’s disease, anorexia, depression, dystonia, epilepsy, essential tremor, gait dysfunction, Huntington’s disease, minimally conscious state, obsessive compulsive disorder, pain, Parkinson disease and Tourette syndrome. In the next step, they listed the stimulation sites, both deep in the brain or on the surface of the brain that was found to have been effective for the treatment of each of the 14 diseases.

In order to test the hypothesis that the various stimulation sites in the brain are different spots within the same brain network, Fox's team used a data base of functional MRI images and a technique that enabled them to see correlations in spontaneous brain activity. These correlations helped the investigators in creating a map of connections from deep brain stimulation sites to the surface of the brain. When this map was compared to sites for noninvasive brain stimulation on the brain surface, the two matched.

The study suggest that understanding the brain networks can help in understanding why brain stimulation works and how these therapies can be improved by identifying the best place to stimulate the brain for a given patient suffering from a given disease. These findings also suggest that resting-state functional connectivity can be useful for translating therapy between treatment modalities, optimizing treatment and identifying new stimulation targets.




anti inflammatory patches

Arthritis is an inflammation of one or more of your joints. You can experience pain or stiffness in the joint area that gets worse as you get older. Arthritis is very common and there are over 3 million cases of this condition in the U.S. alone.


When you were younger you may have thought that arthritis was a condition that only affected older people but people can experience arthritis from birth and for the rest of their lives. Do you suffer from some form of arthritis? Do you wish to experience relief without trying a bunch of medicines prescribed by your doctor?


Many different treatments are now available for people with arthritis and the symptoms that go along with it. If you have already tried losing weight and exercising more but noticed it caused more pressure on your joints you aren't alone. Many people are enjoying the benefits of massages, acupuncture and hot and cold therapy to relieve their swelling and pain.


Something that people may not have known is available to them is anti inflammation patches. Patches that are bought over the counter can be placed on the body to feel relief from arthritic symptoms.


Different types of arthritis


According to the Arthritis Foundation, there are over 100 different forms of arthritis and related diseases. The main arthritic diseases and conditions are osteoarthritis, rheumatoid arthritis, psoriatic arthritis, fibromyalgia, gout, lupus, back pain and other musculoskeletal pain.


Osteoarthritis is where the protective cartilage inside of the joint breaks down. Over time the bones of the joint may end up rubbing against one another causing extreme pain.


Rheumatoid Arthritis is a condition where the joints and organs are attacked by your body's own immune system. RA is an autoimmune disease and the disease will attack the healthy tissue. When you have RA the immune system will mainly attack the lining of the joints.


Psoriatic Arthritis is an autoimmune inflammatory disease where the immune system attacks the body and therefore causes it inflammation and pain.


Fibromyalgia is a central pain syndrome, this means that the brain and spinal cord will process pain signals differently. With this condition something that feels mild may feel more painful and it is characterized as widespread pain.


Gout is a form of inflammatory arthritis and it is an excess build up of uric acid that will form crystals in your joints.


Lupus is an autoimmune inflammatory that affects your joints, kidneys, blood, skin, brain and other organs. It can cause kidney problems, hair loss, joint pain, fever, rash and a sensitivity to light.


What is arthritis inflammation?

Do you experience swelling because of arthritis? Swelling is an enlarging of the skin, organs or other body parts because of a build up of fluid or an inflammation. Inflammatory arthritis is a term that describes several conditions that affect your immune system.


Arthritis doesn't always have inflammation involved. Any sort of inflammation is part of the body's immune response, meaning the body is trying to heal itself. Chronic inflammation can cause conditions like rheumatoid arthritis.



What do people usually use for arthritic pain and swelling?

When it comes to pain management people will use almost anything to not feel bad. NSAID's or Nonsteroidal anti-inflammatory drugs are used to help reduce pain and swelling. Most of these NSAIDs are in the form of creams and gels so that they can be rubbed in to the joint area.


People are using these NSAIDs along with some form of pill like ibuprofen to help pain in general. People with arthritic pain are used to having to do 2 or more things to get relief. With a patch they would only have to do the one thing.


How do patches work?

Transdermal patches are patches that stick to the skin and transfer medicine through the patch in to your skin. Not all medicines or drugs can be administered this way but it does allow for that drug to get through the skin layers and in to your bloodstream in a specific dose. Using a patch also allows for medicine to get in to your body without having to go through your stomach which may be sensitive to medications.


Drugs that are commonly administered transdermally are:


  • Nicotine
  • Opioids
  • Antianginal- Heart
  • Antidepressant
  • Transdermal Ritalin
  • Anti-nausea
  • Estrogen and testosterone
  • Contraceptive medication
  • Blood pressure medication
  • Alzheimer's treatment



What kind of patches can be used for arthritis swelling and pain?

There are different types of patches that can help with the swelling and pain for arthritis but anti inflammatory patches can keep working for 24 hours or longer. This means that someone who suffers with pain and swelling wouldn't need to take a pain reliever when they had one of these patches on. Stamina Pro anti inflammatory patches, which were created to help out athletes starts working within 15 to 20 minutes causing the inflammation to go down and pain and swelling get relieved.


A patch like this is natural and can be placed in a place that you are comfortable having it. It also allows you to have relief in a cost effective way where you don't have to think about taking more or extra. With a patch you are able to put it on your body right after you take your morning or nightly shower and you don't have to worry about it until the next day.

Foods that fight inflammation?

If you are looking for a little something extra you can do to help fight your inflammation there are different foods that you can eat.


13 anti-inflammatory foods

  1. Berries– Berries are packed with anthocyanins, which are antioxidants. These properties may reduce inflammation.

Here are some of the most eaten berries:

  • Strawberries
  • Blueberries
  • Raspberries
  • Blackberries


  1. Fatty Fish– Fatty fish are a huge source of omega 3 fatty acids, DHA and EPA, these have anti-inflammatory properties.

These fatty fish are common sources:

  • Salmon
  • Sardines
  • Herring
  • Mackerel
  • Anchovies


  1. Broccoli– Broccoli is high in an antioxidant called sulforaphane, which is powerful anti-inflammatory effects.



  1. Avocados– Avocados are a great source of healthy fats and antioxidants that protect against inflammation.


  1. Green Tea– Green tea is high EGCG, which is a potent antioxidants with that content reduces inflammation.


  1. Peppers– Bell peppers and Chili peppers are rich in sinapic acid, ferulic acid and other antioxidants that have strong anti-inflammatory effects.


  1. Mushrooms– Mushrooms are rich in anti-inflammatory properties and it's compounds may decrease inflammation.


  1. Grapes– Grapes have many antioxidants including resveratrol, which can reduce inflammation.


  1. Turmeric– Turmeric contains curcumin, a powerful anti-inflammatory compound. It can relieve muscle and joint pain.


  1. Extra Virgin Olive Oil– Extra virgin olive oil provides powerful anti-inflammatory properties because of the antioxidants that it has.


  1. Dark Chocolate and Cocoa– The flavanols, which are potent antioxidants are in dark chocolate and cocoa, can reduce inflammation.


  1. Tomatoes– Tomatoes are high in lycopene, vitamin C and potassium which may help reduce inflammation.


  1. Cherries– Sweet and tart cherries can reduce inflammation because of the antioxidants in them. Eating cherries can reduce pain from arthritis and post exercise soreness.


Arthritis can be a painful condition and a debilitating disease but it doesn't have to ruin your life. Thankfully there are many things that you can do to keep your inflammation, pain and swelling at bay.


Definitely pay attention to what you are eating and if it may be causing your inflammation to be worse than usual. You also have to do some sort of exercise, even if it is just walking. Your body needs you to keep moving because the entire body benefits from exercise.


If you want to pamper yourself with a massage or some acupuncture that's perfect. These two things are not only great for your body, your circulation and your mental health. Plus, these are just amazing for stress relief even when you aren't dealing with swelling or pain.


Ease your mind by doing meditation that can allow you to get in alignment with your body and heal it from a mental standpoint. You also have the patches that you can add in with all of these other things for pain management, swelling and inflammation. You don't have to be stuck taking 2 or more medications to help you deal with your arthritic problems anymore.

If you're trying to lose belly fat, it is important that you include some of the important super foods in your diet. These super foods will help you to lose belly fat. So, if you want to lose belly fat, it is very important to include these super foods in your diet.

Peanut butter

Peanut butter is a superfood that will help you to lose belly fat. It contains 8 g of protein and up to 4 g of fibre per serving and so it becomes an ideal snack which will not only help you to fill up but will also to stay satisfied. It contains L-arginine which is an amino acid that improves your blood flow throughout the body and relax your blood vessels. It will help you to find a solution for the problem of fluid retention.


Pumpkin is important because it contains more fibre than quinoa and more potassium than a banana. You can consume the vegetable or can use the pumpkin puree. The puree can be used in snacking and cooking. You can substitute sweets with a home-made preparation where you use pumpkin puree with unsweetened Greek yoghurt, cinnamon and chopped pears.


Yes, chickpeas can help you to lose belly fat and it is a very important superfood. It contains lots of fibre and plant-based protein, bloat busting minerals and immune boosting antioxidants. It's also easy to eat because it can go in your soups, stews, salads and side dishes. You can also use chickpea flour in your baking as it is nutrient dense and also very filling.


You need more protein if you are trying to lose weight and lean protein is very beneficial for you. Tuna provides you with healthy protein. Salmon and sardines are also good for you. There are full of important omega-3 fatty acids and lean protein. It will not only help you to carve craving but will also help you to feel full.


Like chickpeas, peas also good for you when you're trying to lose weight. A cup of peas contain 8 g of protein and lots of bloat reducing nutrient. It will give you your daily quota of vitamins C along with magnesium, potassium and iron. These are good for you because they will help you to counterbalance sodium and will also help in to bring more oxygen to blood cells.

Fermented foods

This is another superfood which should be included in your diet you really want to lose weight. Miso, Tempeh and sauerkraut are some of the examples of important fermented foods. They contain probiotics or friendly bacteria which will help you to boost your immune system, regular cut function and beat bloating. You can also try unsweetened plain Greek yoghurt and skyr because they also provide probiotic benefits.


even though it may seem that potatoes are not good for you when you're trying to lose weight and fat, instead potatoes are good for you when want to lose weight. Baked potatoes will provide you with lots of potassium. Potassium is necessary for counterbalancing sodium and beating bloat. Potatoes contain lots of filling fibre and so you will feel full for a longer duration. However, while consuming potatoes, you should avoid the deep fried ones. It's a nutrient dense food and good for you but you should stay away from the French fry.


1. Eden Diet
2. The Belly Fat Study
3. Abdominal fat and what to do about it

Heart disease is the leading cause of death around the world and high cholesterol levels is one of the main causes of heart disease.

Oxidised cholesterol

Cholesterol is a wax like substance which is naturally present in your body and the body needs it for proper functioning. Build-up of cholesterol on artery walls is dangerous. When this cholesterol is oxidised you get oxidised cholesterol. Oxidation is the result of a normal body process and oxidise cholesterol in limit is not a problem for you but if because of a trigger somehow overproduction of oxidised cholesterol happens, it can be dangerous. Your body's immune system may mistake oxidised cholesterol for bacteria and then can try to fight it off. If that happens, there will be inflammation inside of the arterial wall and that can result in atherosclerosis or heart disease.

How do they form?

The oxidation of cholesterol happens when cholesterol particles present in your body react with free radicals. Free radicals are produced in your body as a result of normal metabolism, exposure to toxins or from disease. These free radicals cause oxidation which is like a chemical destabilisation of molecules. The oxidised cholesterol then becomes more reactive with the surrounding tissue and that reaction results in inflammation. Such inflammation can result in disease and organ damage.

The chance of oxidation increases because of the following reasons-

  • Consuming a diet that is high in trans fats
  • Smoking
  • Poorly controlled diabetes
  • Metabolic syndrome, which is often a precursor of diabetes
  • Exposure to toxins through pollution and preservatives
  • Stress

The oxidised cholesterol can inhabit the endothelium or the inner lining of the arteries in your body. They are found in the carotenoid arteries, the coronary arteries or the arteries that provide blood to your legs and arms.

The effects of oxidised cholesterol

The oxidised cholesterol that are present in the arteries can be dangerous for you because of the inflammation. Since the blood vessels carry blood to different organs and tissues of your body, the inflammation can stop such supply and may result in a heart attack or a stroke.

The oxidised cholesterol present in the inner lining of the arteries result in a compilation of inflammatory cells. Along with them, platelets which normally helps in stopping bleeding by producing clots, may create plaques in the artery. These are hardened areas inside a blood vessel. Once they are formed, cholesterol, other lipids and macrophages begin to accumulate that area and the plaque gradually grows larger. In that case, partial or complete restriction of blood flow may happen in an artery and that can result in different types of health problems including coronary heart disease, peripheral vascular disease or cerebrovascular disease.

Preventing oxidised cholesterol

It is possible to prevent oxidise cholesterol by focusing on eating healthy fats. Monounsaturated fats are considered anti-inflammatory and they are good for your health. If you're eating saturated fats, it should be done in moderation. You should include more fresh fruits and vegetables in your diet. You should also pay attention to nutrition labels because it is important to stay away from hydrogenated or partially hydrogenated foods. Natural supplements and a healthy diet is the best method of staying away and preventing oxidise cholesterol and the effects of this problem on your overall health, especially cardiovascular health.


1. The Oxidized Cholesterol Strategy
2. Cholesterol
3. High Blood Cholesterol

The purpose of facial exercises

Your face has more than 50 different muscles. Even though you use different muscles in your body a different point of your time but the facial muscles are rarely used. Since we do not do any exercises for the face so these muscles are left untouched.

When you start regular facial exercises, you promote the circulation of blood to different areas of your face. When that happens, the blood will replenish the oxygen supply in the muscles and the skin. It will help you to achieve a bright complexion and beautiful healthy glow.

When you perform regular facial exercises it'll keep your facial muscles fit for the long-term. Regular facial exercises will improve the blood flow and provide your skin cells with nutrients which will result in stimulation of cell regeneration and prevention of wrinkles.

How often should you exercise your facial muscles?

This is a very important question. You need to perform facial exercise routine 3 to 5 times a week for about 20 minutes. This is one of the quickest way to see results and within a couple of months you will start to see changes to your complexion.

Benefits of facial exercises

  • When you perform regular facial exercises, it will strengthen the muscles in your face.
  • Regular facial exercises will reduce the appearance of wrinkles
  • Regular facial exercises will also increase blood circulation in your face, different cells and will provide the necessary nutrients.
  • Facial exercise will also release any tension in the face and neck.
  • Regular facial exercise is necessary to ensure that you have a firm and tight facial skin.

Facial yoga

Facial yoga is another type of exercise for your face. However, unlike some other facial exercises, facial yoga is focus on relaxing and toning your face. It is very similar to yoga because like yoga it also tries to relax you and improve your body. Facial yoga is beneficial for you because it intends to counteract the effects of strained facial expressions to leave both the muscles and skin relaxed and rejuvenated.

There are different types of facial yoga exercises which you can do to get benefit from them for a long time. One simple example of facial yoga exercise is simply rubbing your hands together to warm them up before placing your palms over your closed eyes. Keep the palms there for a few minutes. While doing this, keep your breath deep. This will help you to relieve any tension from the eye area.

Some tips for performing facial exercises the right way

If you are trying to perform facial exercises to improve your face, the following tips will help you to do better and get more benefit.

  • You need to perform facial exercises lying down because they are most effective at that position.
  • Before you start facial exercises, you should only clean your hands. If you touch your face with unclean hands, it can result in contamination and infection which will result in different skin problems.
  • If it is possible you should try to do your facial fitness routine at the same time every day. This will help you not to forget to perform your facial fitness routines every day.
  • While performing facial fitness routine, you should never pull or tug on the skin aggressively. If you do that, it can get you the opposite result- it may accentuate wrinkles.


1. Face Engineering Exercises
2. The effectiveness of facial exercises for facial rejuvenation: a systematic review
3. Facial attractiveness: evolutionary based research


It is no more surprising to hear from you friends that they have had a medical trip abroad. People choose to undergo treatment in another country in the search of unavailable in their own city equipment, unique techniques, or innovative medicines. Other possible benefit is privacy (no one will ever know about your disease, unless you decide to tell about it) and high level of comfort.


According to the Report on World Tourism Economy Trends 2019, provided by the authoritative organization World Tourism Cities Federation, Germany ranks third in the list of the most popular among the patients countries. First places are occupied by the USA and China that are less attractive for European people.

German healthcare system offers comprehensive prophylactic examination (check-ups), individualized treatment, rehabilitation programs for adults and children. In addition, German doctors are ready to admit patients with complex diagnostic cases and rare disorders. A number of specialized competence centers are functioning on the basis of German hospitals, for instance National Center for Tumor Diseases, Heidelberg and Neuroscience Research Center in Charite University Hospital, Berlin.

Process of treatment in Germany

Medical program in any German clinic always starts from the detailed examination. Clarification of the diagnosis with high-tech equipment and laboratory reagents can completely change the initial diagnosis or planned treatment. For instance, tests can reveal less advanced stage of the ischemic heart disease that does not require stenting and may be treated by conservative means. Or vice versa, PET-CT may reveal more advanced cancer stage that requires additional metastases removing.

Examination is performed in 1-2 days, without long waiting periods. Based on the actual health information, treatment is planned and performed. There is great diversity of the therapeutic techniques, but all of them are aimed at maximal safety and comfort for patients. German healthcare is famous for minimally invasive surgical interventions and painless postoperative period.

The treatment program is followed by obligatory rehabilitation. Rehabilitation is a process of coming back to usual everyday life and learning to live with the disease consequences (if there are any). Being initiated at the healthcare facility, rehabilitation program continues at home. In addition, patients receive detailed recommendations on relapses prevention. These include lifestyle modification (e.g. avoiding tobacco products and alcohol), special eating habits, physical activity, drugs and vitamins intake, etc.

Cost of treatment

When planning the treatment budget, you should always check your insurance policy. Certain insurance companies include receiving medical treatment in Germany in the list of allowed procedures. When the situation is urgent (you actually did not plan to undergo the therapy abroad but need to do this for health reasons), you should check if you have a European Health Insurance Card (EHIC), a kind of the traveler's insurance. Owners of the EHIC can receive free or partially compensated healthcare services.

In other cases you will have to pay the full price in the final calculation by yourself. Costs will vary greatly depending on the hospital and required intervention. For example, price for the platinum coils embolization in brain cavernoma in the University Hospital Saarland, Homburg is 16,300 € while in the Charite University Hospital, Berlin it reaches 33,300 €. Conservative therapy is always cheaper than the invasive intervention. For example, medicamentous treatment of hip osteoarthritis starts from 1,075 € and the joint replacement (endoprosthesis) from 8,300 €.

Choosing the best price / quality of treatment ratio may be tricky if you have no relevant experience. You may start exploring this question and spend heaps of time, or entrust the solution of this issue to the professionals certified medical tourism operator Booking Health.

Arrangement of treatment abroad

Aim of Booking Health is providing each patient with necessary medical services in the most appropriate hospital for the affordable price. The company arrangestreatment abroadin a number of countries, including Austria, Switzerland, Turkey, Israel, Thailand, Poland, South Korea, etc. Special attention is paid totreatment in Germany, as this country offers the most favorable treatment and rehabilitation results, attractive prices and high comfort of staying.

Booking Health professionals accompany a patient during the whole treatment process. First, doctors carefully investigate available medical reports, check patient's complaints and discuss possible options. Then they offer one or few hospitals that best meet established treatment goals.

After final agreement on the hospital and treating physician, the precise appointment date is booked. A patient should get ready in advance issue visa (administration of the clinic will sent the invitation for treatment, if necessary), take care about the passport expiry date, choose the most suitable way to travel (e.g. by plane, car, etc.). Qualified interpreters of Booking Health will translate all valuable medical reports into German, in order to avoid repetition of examinations.

Patient's personal coordinator will take care about booking tickets and accommodation, transfer from the airport, interpreter services. Medical specialists of Booking Health will independently monitor the process of treatment and give advice. Financial specialists of Booking Health will control all the expenses, avoiding additional fees and overpricing. Should you leave the request on the Booking Health website, the process of treatment abroad will become easy and comfortable.

If you are suffering from back pain there may be different ways of getting relief but one of the most efficient method of back pain relief is exercise. Specific exercises when done regularly can help you to get immediate relief and most importantly long time relief.

Let's find out why you need exercise for back pain relief.

Exercise helps you to recover

Most of the back pain isn't serious and if that is the case with you, it'll be possible for you to exercise even when you have back pain. You should continue your daily activities even when you feel a bit of pain in the back. If you walk in the morning, walk your dog or you go for little running in the morning, he should continue doing that. If you pain is severe and you cannot withstand it, if you have tingling, numbness or weakness in your legs or if you experience any bladder or bowel issues, then only should go and see your doctor. Otherwise, you should continue with your regular exercise because in the long run regular exercise will help you by improving your core and spine strength, which are very important for a better back health.

Yoga is like a gentle back massage

With its twisting, turning, asanas and mudras, yoga provides relief from different types of pain and it works for long time. Breathing techniques, relaxation and soothing poses will help your spine in a great way. Scientific studies have found different benefits of yoga which include both physical and mental benefits. To practice yoga for three months, it will not only prevent back pain and other pain problems but it will also help you to get relief from existing back pain. Simply practising yoga three days a week will do wonders to your body.

Running is important for your spine

Running strengthens your spine and that is why you need to keep running if you want to avoid back pain or if you want to get rid of the little back pain that you have. Regular long-distance running regimen will improve the health of intervertebral discs by keeping them nourished and hydrated. These discs are important because they help you to absorb shock to the spine. Jogging, speed walking and regular walking will also help you to strengthen your spine.

Core works will keep you stable

It is also important to go for core exercises because the health of your core is very important for the health of your back. Core exercises does not mean they are roundly for the six-pack. If you want to alleviate chronic lower back pain, core strengthening is what you need. It is in fact superior to resistance training in case of chronic lower back pain. The muscles of your midsection include those in the front of your body, the muscles present in your back and around your spine along with hip muscles, diaphragm and pelvic floor. These are some of the deep, supporting muscles which will help you by stabilising your back as you move. If you can make those muscles strong, you won't suffer from back pain and if you're already suffering from it, strengthening these muscles will help you to get relief in the short and in the long run.

Increase total body strength

If you do prevent back pain and if you want to get relief from existing back pain, you need to create a program or find one that combines strength training and walking or any cardio. Such a program will not only reduce pain but it will also boost your spinal function.


1. My Back Pain Coach
2. Back Pain
3. Low Back Pain Fact Sheet