Home Life Style Limiting The Production Of Endocannabinoid Compound Can Boost Fat Burning

Limiting The Production Of Endocannabinoid Compound Can Boost Fat Burning


Endocannabinoid Compound

Although it seems impossible, new research showshow a person could lose weight without anyexercise and without adopting any drasticdiet. This discovery, tested on mice by Italian andUC Irvine Researchers, is based on limiting the brainproduction of a compound called endocannabinoid 2-AG. Dr. Daniele Piomelli, one of the world’s leading endocannabinoidresearchers, thinks the endocannabinoid2-AG production limitation can induce a state of hipercatabolismthat would help people lose weight. So far the resultsof thestudyare verypromising.

Researchers found that mice who consumed more fat and exercised lessthantheir peers have not gained weight. In addition, despitea high calorie diet and asedentary lifestyle, tested mice did not develop metabolic syndrome, a complication that generally occursunder these conditions.

Abdominal Fat and Metabolic Syndrome

Abdominal Fat and Metabolic Syndrome

The fact that mice have not gained weight has an explanation: tested miceburned fatquickly and more calories than normal mice.Itis awell-known factthat endocannabinoids play a key role in energy dissipation, but only now scientists have discovered a target where this occurs. Mutant mice, whose production of 2-AG was limited, have kept their weightdue tobrown fat which became overactive. Brown fathas more mitochondria in contrast to normal adipose tissue.Up until recently, people thought that this type of fatwas found only in young children in order to provide heat. Recently, researchers found thatbrown fat is alsopresent in adults, but in smaller amounts. This type of fat has also been considered a new weapon against obesity asresearchers found that obese personshave less brown fat than normal weight counterparts.

Endocannabinoidsare compounds produced naturally in the body, which contain a chemical structure similar to that of marijuana, namely cannabis. Endocannabinoidslinked to cell receptors, called cannabinoid receptors,which are involved in various processes, such as the body’s response to pain, appetite ormood. Also, endocannabinoidsare responsible for unruly appetitefrom food, especially to those that contain fat. When fatty foods arrive in the gut, a group of cells in the digestive system releases endocannabinoids, a phenomenon which does notoccur when eating proteins or sugars. Scientists believe that this mechanism involves the release of digestive compounds linked to hunger and satiety and therefore one feelsthe needto eat more.

However, according to Piomelli it isimpossible to create a drug thatblocks production of 2-AG in humans. At most, researchers will try to produce a drug that determinesthe brain to produce fewer endocannabinoids. Therefore, sports, diet and healthy lifestyle are still the key to success in the fight against obesity.