Green Tea Molecule breaks up harmful protein plaques in blood vessels.
Green tea can be the vital thing to ending deaths from heart attacks and strokes brought about by atherosclerosis. This was according to a study published in the Journal of Organic Chemistry.
Experts from Lancaster University and the University of Leeds have exposed that a compound discovered in green tea, presently being studied for its capability to shrink amyloid plaques in the brain in Alzheimer’s disease, also breaks up and liquifiesdamaging protein plaques discovered in blood vessels.
Atherosclerosis is the assembly of fatty deposits within our arteries that may stop the flow of blood to the brain and other parts of the body. In majority of cases, a protein known as apolipoprotein A-1 (apoA-1) can form amyloid deposits, which are alike in structure to those linked to Alzheimer’s disease. These deposits build up within atherosclerotic plaques. There, they surge the size of the plaques, further restricting blood flow and may also make the plaques much less steady, growing the chance of a heart attack or stroke.
Epigallocatechin-3-gallate and Amyloid Plaques
Investigators found that epigallocatechin-3-gallate which is related to green tea, binds to the amyloid fibres of apoA-1. This alters the fibres to smaller soluble molecules that are less likely to be unsafe to blood vessels.
Now, the teamis working on discovering ways of presenting strong quantities of EGCG into the blood without having to drink enormous quantities of green tea. This could involve adjusting the chemical structure of EGCG, making it easy to be absorbed from the stomach and more resilient to metabolism, or creating new methods to provide the molecule to the plaques such as by injection.
The researchers commented that the health and wellness advantages of green tea were generally endorsed, and it has been identified for some time that EGCG can modify the assemblies of amyloid plaques related to Alzheimer’s disease. The outcomes of this study have shown that this intriguing compound would also be effective against plaques which can cause heart attacks and strokes.
They further added that our bodies are very good at breaking down EGCG so substituting your cupfor green tea is not likely to make a huge alteration with respect to your heart health. However with the help of engineering the molecule fairly, they may be capable of making new drug treatments to deal with heart attack and stroke.
The findings of these reports are very encouraging, they commented. Scientists now need to apply the great scientific tactics to seek out how we can take the molecular EGCG aspectof green tea and turn it into a functioning strategy to fight life-limiting health disorders.