Home Life Style Liraglutide May Decrease the Risk of Heart Disease

Liraglutide May Decrease the Risk of Heart Disease

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What Is Heart Disease?

Heart disease is any type of disease that affects the heart. It may also be referred to as cardiovascular disease or medical conditions that involve the blood vessels and the heart. Heart disease is said to be the leading cause of death in many countries. These heart diseases may include angina, arrhythmias, congenital heart disease, coronary artery disease, cardiomyopathy, heart failure, myocardial infarction and many others.

Angina is a heart disease which causes chest discomfort, tightness or pain. This condition is caused by a lack of oxygen on an area of the heart muscle caused by narrowing of the arteries of the heart because of plaque accumulation (atherosclerosis). Arrhythmia, on the other hand, causes irregularity of the heartbeat as what is found in tachycardia (fast heart beat), bradycardia (slow heartbeat), premature contraction and fibrillation. They happen when the heart's electrical signals do not work properly and beat either faster than normal or slower than normal. Congenital heart disease is a birth defect that involves the heart; examples include septal defects (a hole between the two chambers of the heart, obstruction defects (the flow of blood through various chambers of the heart is partially or even totally blocked and cyanotic heart disease (caused by not enough oxygen pumped around the body). Coronary heart disease happens when the blood vessels that supply the heart become diseased or damaged because of plaque deposits made up of cholesterol. Plaques lead to narrowing of the arteries, making the heart get lesser than normal oxygen.

Dilated cardiomyopathy, on the other hand, is a condition wherein there is dilation if the heart chambers because of weakened heart muscle. Myocardial infarction is also known as heart attack and is due to an interruption of blood flow that damages or destroys the heart muscle. This is usually caused by a blood clot that develops in one of the blood vessels that supply the heart. Heart failure is a medical condition wherein the heart does not pump enough blood to the other parts of the body due to coronary artery disease or hypertension.

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Another heart disease is hypertrophic cardiomyopathy, a genetic disorder in which the ventricles become thicker making it difficult for the blood to leave the heart and making the heart pump harder. This can lead to sudden death. Another heart disease, mitral regurgitation, occurs when the mitral valve of the heart does not tightly close, allowing blood to flow back into the heart. Mitral valve prolapsed is a heart disease wherein the valve between the left atrium and left ventricle does not fully close or prolapses upwards or towards the atrium. Still another heart disease, pulmonary stenosis is a heart disease wherein the heart finds it hard to pump blood from the right ventricle into the pulmonary article because the pulmonary valve is too tight; this pushes the right ventricle to work harder to overcome the obstruction.

Liraglutide May Decrease the Risk of Heart Disease

A recent study has shown that treatment with the diabetes drug liraglutide, in combination with diet and exercise, led to a significant reduction in weight and improved a number of cardiovascular risk factors, including high blood pressure and high cholesterol. This multicenter study gathered data from more than 3,700 overweight and obese nondiabetic adults; its results were presented at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago. The drug is undergoing testing at a 3 milligram (mg) dose for long-term weight management as part of the SCALEâ„¢ (Satiety and Clinical Adiposity — Liraglutide Evidence in Nondiabetic and Diabetic Subjects) Obesity and Prediabetes trial. Liraglutide currently is marketed as Victoza® in 1.2 mg and 1.8 mg injectable doses for adults with Type 2 diabetes to help control blood glucose (sugar) when used along with diet and exercise.

More medical breakthroughs can be found on the other articles of this site.