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Stem Cell Transplant

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Stem Cell Transplant

What is stem cell transplantation?

Stem cells are defined asundifferentiated cells that areable to transform into anyhigh specialized cellwhich canlater form any type of tissue and organ in the humanbody. They are soimportantdue totheir ability to differentiate into virtualany cell type.
Cord blood stem cellsare able totreatnumerous forms of malignant blood diseases.We include hereleukemia, usingatreatment with the patient’s own cells. Stem cell transplantation is defined ashealthy infusion of stem cells, and is required if the number of stem cells that are produced by bone marrow is low or the bone marrowno longer fulfills its functions properly. Stem cells are designed to produce healthy condition white cells, platelets and red blood cells thereby minimizing the patient’s risk of suffering fromvarious infections and anemia.

Regarding stem cell source, we can talk about stem cell transplant that uses the patient’s own cells (autologous transplant), and stem cells from a donor, in which case we are talking about allogeneic stem transplantation.

Treatment with stem cells is very useful for treating patients whose stem cells were affected bya disease, whether it is cancerous or noncancerous process involved. The stem cells can also be used to replace diseased bone marrow. Bone marrow produces too few blood cells in this case and new stem cells willbetransplanted that will replace thenon-functional bone marrow, which willeventually start functioning normally. In the case of leukemia, cancer cells present in the patient’s bone marrow can beremoved alsowith the help oftransplanted stem cells. After a stem cell transplant, the production of normal bone marrow cells can be resumed.

Stem Cells

Stem Cells

What are the risks?

Stem cell transplantation is nota procedure without complications, unfortunatelymany of them can be even fatal. Many patients donot meet major problems, but some are forced to perform multiple tests and be hospitalized to benefit from this type of procedure. Among the most common complications we mention: failure of the transplant, graft versus host disease, lesions of different blood vessels, cataracts, the occurrence of secondary cancers or even death. The patient should know the risks andin conjunction with hisdoctorshould balance the benefits and complications andthen make the right decision. The greatest danger is the possibility of transplant rejectionwhenthe transplantedstem cellsare comingfrom adonor, condition called graft versus host disease.